Out of the Box Course Overview

Thank you for your purchase of the Marijuana Education Initiative Out of the Box lessons.

Here are Instructions on how to use your lessons:

All of the instructions and activities to teach the MEI Out of the Box lessons are included in the booklet.

Links to the supplies, printable worksheets, and optional video clips for each of the lessons can be found below.

Please check back on our website often for any updates to lessons. As new marijuana information and research become available that could affect the content of the lessons.

Locks and Keys; How THC works in the brain


  • Youth understand how the THC in marijuana “locks in” to receptors in the brain and modifies behavior, memory and cognition.
  • Youth understand that the brain is designed to receive specific neurotransmitters that THC can mimic.
  • Youth understand that the brain is always trying to maintain a healthy amount of chemicals and too much of a certain chemical from an outside source will cause a brain to become dependent.


Lock and Key Set (order 3 sets)

Anandamide vs THC image

The Endocannabinoid System; Everyone Has One


  • Youth understand the areas and functions of the brain most affected by marijuana use.
  • Youth understand the areas of the brain where the endocannabinoid system has the highest concentration of cannabinoid receivers.


Brain stress ball for each student option 1, option 2

1520 short, colored pushpins for each student (recommended package comes with 100 pins)

Cannabinoid receptors in the brain image

Hole Lotta Nothin’


  • Youth understand the areas of the brain most affected by marijuana use.
  • Youth understand that blood flow to the brain is essential to healthy cognitive functioning.
  • Youth understand that marijuana use in adolescence can affect activity and blood flow in important parts of the brain.


Brain stress ball for each student option 1, option 2
(can be the same one used in the Endocannibinoid lesson above)

2 Amen Clinic brain images pdf (preferably printed in color and laminated) One, Two 

Executive Function Roulette


  • Youth understand the executive function skills associated with the frontal lobe.
  • Youth understand how chronic marijuana use during youth affects the frontal lobe.
  • Youth understand how chronic marijuana use during youth affects executive functioning skills.


Blank game spinners (make the “0” into a “10”)

Copy of Executive Function worksheet for each student

A pen or pencil for each student

Straw Breathing


  • Youth understand the impacts marijuana use has on the lungs.
  • Youth identify the respiratory conditions attributed to chronic marijuana use.


A large drinking straw for each student

Lung Glove


  • Youth know the substances that are common in cigarette and marijuana smoke.
  • Youth know the substances that are found in a vaporizer or e-cigarette.
  • Youth understand how the plant substance changes into a gas and particulate substance.
  • Youth identify three of the substances that enter the lungs when someone inhales smoke or vapor from an e-cigarette or marijuana vaporizer.


Paper towels

Propylene glycol


Latex gloves

Liquid pine tar

There should be enough materials in this order to teach this unit five to seven times. You might want to order double the amount of pine tar to have enough to teach the activity 10+ times.

Where else does marijuana go?


  • Youth understand that marijuana (and other drug) use affects the entire body system.
  • Youth understand that different modalities marijuana use affect the organs differently.
  • Youth understand that marijuana use leaves residual deposits of the chemical throughout the entire body.


A copy of the body outline
A white paper towel for each student
A sharpie marker for each student

Pin the Part


  • Youth understand the parts of the body that are affected by marijuana use
  • Youth understand how different methods of marijuana consumption can affect the different body parts.


Copy of the body outline

Cut outs of the pin the part organs

Push pins or tape

Norms of Use


  • Youth understand that not “everyone is doing it” in regards to marijuana use.
  • Youth have a clear understanding of actual rates of marijuana use among their age group to validate their attempts to abstain or delay their own marijuana use.


Copy of the norms of use handout

Marijuana Labeling and Edible Awareness


  • Youth understand common labeling images to indicate an edible item has marijuana in it.
  • Youth understand why it is important to ask a trusted adult before eating an item that could potentially have marijuana in it.


Popsicle sticks (4 for each student)

Copy of the sign art document

THC, CBD, and Potency


  • Youth understand that different forms and strains of marijuana have different proportions of compounds.
  • Youth understand that different proportions of cannabis compounds have different effects on the user.


Small plastic baggies OR small clear test tubes (preferred)

Salt and pepper packets

Free from Dependence


  • Youth understand the common criteria of marijuana addiction and dependence.
  • Youth understand the addictive properties and of marijuana and rates of use.


Water glasses/cups

Support Chain


  • Youth know the people they can count on for support in abstaining from using marijuana.
  • Youth know the strengths they have that will help them abstain from using marijuana.
  • Youth know the reasons they have for abstaining from using marijuana.


Precut strips of paper in three different colors (construction paper works best); 1″ × 8.5″ strips

Stress Hammock


  • Youth identify stressors in their lives.
  • Youth identify healthy activities that alleviate stress.
  • Youth identify an unhealthy activity that offers the perception of alleviating stress.



Ball of yarn

Blank sticker name tags

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